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Gangliosides in a Sentence
  • Gangliosides are fatty substances necessary for the proper development of the brain and nerve cells (nervous system).
  • Under normal conditions, gangliosides are continuously broken down, so that an appropriate balance is maintained.
  • In Tay-Sachs disease, the enzyme necessary for removing excess gangliosides is missing.
  • This situation allows gangliosides to accumulate throughout the brain and is responsible for the disability associated with the disease.
  • Without this enzyme, gangliosides cannot be broken down.
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